Amphetamines
StimulantsAlso known as: Speed, Uppers, Adderall, Dexedrine, Bennies
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All content is written, edited, and medically reviewed by licensed professionals with expertise in addiction medicine and behavioral health.
Benjamin Zohar
NCACIP
Nationally Certified Advanced Clinical Intervention Professional and recovery advocate in long-term recovery, specializing in intervention services and treatment coordination.
Ezra Zohar, M.S.Ed.
Educational Specialist
Educational Specialist with M.S. in Secondary Education, reviewing educational content focused on addiction awareness and recovery.
Brandon McNally
RN
Registered Nurse with specialized training in addiction medicine and behavioral health nursing.
Last Updated
November 2025
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Call Helpline: (914) 594-5851What is Amphetamines?
Amphetamines are central nervous system stimulants that increase dopamine and norepinephrine levels. Prescription forms like Adderall are used to treat ADHD and narcolepsy. Illicit amphetamines are abused for their energizing effects. They have high potential for abuse and dependence.
Effects
Increased energy and alertness, euphoria, decreased appetite, increased focus and concentration, elevated mood, increased heart rate and blood pressure, dilated pupils
Risks & Dangers
Cardiovascular problems, high blood pressure, irregular heartbeat, stroke, psychosis, anxiety, paranoia, aggression, addiction, severe weight loss, dental problems, skin problems
Withdrawal Symptoms
Depression, fatigue, increased appetite, sleep problems, anxiety, drug cravings, agitation
Addiction Potential
High - Amphetamines are highly addictive. Tolerance develops with regular use, leading to increased doses.
Duration
Effects typically last 4-6 hours for immediate-release, longer for extended-release formulations
Legal Status
Schedule II controlled substances in the US. Legal with prescription, illegal for non-medical use.
Alcohol Interaction Warning
Mixing Amphetamines with alcohol can be extremely dangerous and potentially life-threatening. Combining substances increases the risk of:
- • Respiratory depression and overdose
- • Unpredictable effects and loss of consciousness
- • Increased toxicity to liver and other organs
- • Impaired judgment leading to risky behaviors
Learn more about alcohol use disorder and polysubstance use.
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Published: July 15, 2024 • Last Updated: November 25, 2025
Medically reviewed drug information for educational purposes
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